Study of High-dose Olmesartan compared with Telmisartan on Blood pressure and Metabolism in Type 2 Diabetics with Hypertensio
- Conditions
- Type 2 diabetes mellitus with hypertension
- Registration Number
- JPRN-UMIN000006046
- Lead Sponsor
- niversity of Occupational and Environmental Health, Japan
- Brief Summary
1) The efficacy of decrease of blood pressure showed no difference between olmesartan and telmisartan. 2)On glucose profiles, olmesartan improved FPG,HbA1c,FIRI and HOMA-IR more effectively than telmisartan. 3)Change rate of hs-CRP is correlated with that of HOMA-IR.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 36
Not provided
1)patients treated with insulin therapy. 2)patients who wrere poorly controlled . 3)patients with secondary hypertension. 4)patients on HD. 5)pregnant patients. 6)patients who wrere allergic to telmisartan and olmesartan. 7)patients with heavy liver dysfunction. 8)patients with heavy renal dysfunction(Cre>3mg/dL).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method