ACTRN12610000311055
Completed
未知
A pilot, randomised controlled trial of retinal artery flicker induced vasodilatation to detect change in endothelial function in participants with obstructive sleep apnoea treated with continuous postitive airway pressure for 6 weeks.
Austin Health Department of Cardiology and Institute for Breathing and Sleep0 sites30 target enrollmentApril 19, 2010
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Endothelial function
- Sponsor
- Austin Health Department of Cardiology and Institute for Breathing and Sleep
- Enrollment
- 30
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Moderate to severe Obstructive Sleep Apnoea(OSA) \- Apnoea Hypopnoea Index greater than or equal to 30, with associated hypoxaemia – Oxygen saturation(Sa O2\) \<90% for a minimumm of 6% of total sleep time.
- •Actual coronary artery disease or two or more of the following cardiovascular risk factors – hypertension, dyslipidaemia, diabetes, smoking, positive family history.
Exclusion Criteria
- •Commercial driver or patients listed for urgent CPAP implementation.
Outcomes
Primary Outcomes
Not specified
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