Prevalence and Risk Factors for the Carriage of Multi- and Highly Resistant Bacteria and Clostridioid Difficile Toxigenic in Residents and Healthcare Workers in Nursing Home (PREMS)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 492
- 试验地点
- 1
- 主要终点
- Presence or absence of multi-drug resistant bacteria in residents' feces.
研究概览
简要总结
Brief summary : Very few studies have evaluated the prevalence of multi-drug resistant (MDR), highly resistant emerging bacteria and Clostridioides difficile toxinogenic (CDt) in residents and in healthcare workers (HCW) in nursing home (NH). Most of study were conducted in acute care services and were limited to specific bacterial species.
Hypothesis : The carriage of MDR bacteria in resident may be a risk factor for an outbreak in NH or in healthcare facility.
Primary outcome: The objective of this study is to estimate the prevalence for carriage of MDR bacteria and CDt in residents in NH.
Secondary outcomes:
- Estimate the prevalence for carriage of MDR bacteria and CDt toxigenic in HCW in NH.
- Identify the risk factors for carriage of MDR bacteria and CDt in residents in nursing home
- Identify the risk factors for carriage of MDR bacteria and CDt in healthcare workers in NH
- Evaluate the presence of cross-transmission of MDR bacteria and CDt in one or several NH
- Evaluate the association between the presence of cross-transmission of MDR bacteria and CDt in a NH and the management of infection control
- Establishment a collection of stool samples
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Presence or absence of multi-drug resistant bacteria in residents' feces.
时间窗: at inclusion (J0)
prevalence of carriage of multi-drug resistant bacteria
Presence or absence of Highly Resistant and Emerging Bacteria in residents' feces.
时间窗: at inclusion (J0)
prevalence of carriage of Highly Resistant and Emerging Bacteria
Presence or absence of Clostridioids difficult toxinogenic in residents' feces.
时间窗: at inclusion (J0)
prevalence of carriage of Clostridioids difficult toxinogenic
次要结局
未报告次要终点