A Comparative Study of Serum Potassium Rate Between Peripheral and Central Venous Sample Collection in Patients With Hypothermia Related Cardiac Arrest
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Comparison of potassium rate in central venous blood and blood from a peripheral vein (measured in mmol/l)
研究概览
简要总结
Serum Potassium Rate (PR) is a key indicator for medical management of patients with accidental hypothermia particularly for hypothermia related cardiac arrest (CA).
Experts recommend a cut-off value for PR of 12 mmol/l for all hypothermic victims and 8 mmol/l for avalanche casualties. Any patient presenting a PR lower than the cut-off value should be considered for Extracorporeal Rewarming. This therapeutic strategy is vital for patient survival.
However, there is no consensus about what type of vessels should be punctured in order to obtain an accurate potassium rate and what type of measurement technics should be used to measure this potassium rate.
The investigators hypothesize that potassium rate in these patients will differ by 1 mmol/l in blood samples collected from a peripheral vein in contrast to a central vein.
The investigators study is a prospective observational, multicentre study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hypothermia related cardiac arrest
- •Age > 18 years
- •Core temperature < 30° C measured in oesophagus at hospital admission
排除标准
- •Age < 18 years
- •Known condition of pregnancy or breastfeeding women
- •Evidence of trauma-related cardiac arrest
- •Cardiac arrest in which reanimation is not justified (frozen body, final stadium of an incurable disease, advance health care directive)
研究组 & 干预措施
Hypothermia related cardiac arrest
blood draw from three different vessels punctured in the emergency room (central vein, peripheral vein, artery) and comparison of potassium rate and other biological values between the different sites of blood draw and two different measuring techniques (laboratory vs. blood gas analyser)
干预措施: blood draw from three different vessels (Diagnostic Test)
结局指标
主要结局
Comparison of potassium rate in central venous blood and blood from a peripheral vein (measured in mmol/l)
时间窗: 24 hours
Comparison of PR in central venous blood and blood from a peripheral vein (measured in mmol/l)
次要结局
- Comparison of potassium rate from laboratory analysis and at bedside via blood gas analyser (measured in mmol/l)(24 hours)
- Comparison of the time difference between laboratory analysis and blood gas analyzer at bed side (measured in minutes)(24 hours)
- Survival and neurological outcome as measured by the Cerebral Performance Category Scale(3 months)
- Study of biological parameters to calculate the Strong Ion Gap (measured in mEq/l) according to the Stewart Approach(24 hours)
- Comparison of potassium rate in venous and arterial blood (measured in mmol/l)(24 hours)