Acute effect of the Sit-Stand Table on Nervous System Control of Heart and Arteries of healthy people: crossover, randomized and controlled clinical trial

Not Applicable

Recruiting

• Conditions: Healthy Volunteers; Sedentary Behavior; Behavior; M01.955

• Registration Number: RBR-7zq9d89
• Lead Sponsor: niversidade Federal de São Carlos (UFSCar)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-06-04
• Last Update Posted: 26 June 2023
• Study Completion: 2023-10-30

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Be between 23 and 45 years of age; work for a period equal to or greater than 4 hours in a seated position and use the computer as their main work tool; not report suffering of chronic health problems; being a non-smoker for more than 1 year; for women, being in the follicular phase, in the period between the seventh and tenth day of the menstrual cycle, i.e., between the end of menstruation and mid-cycle; agreeing to participate in the study; and, not having symptoms of coronavirus disease 2019 (COVID-19).

Exclusion Criteria

Having a physical condition that prevents them from performing postural changes from sitting to standing or standing for more than 20 minutes; having signs and symptoms of pregnancy or being in gestational period; report having cardiovascular diseases [heart failure, coronary artery disease, arterial hypertension, changes in heart rhythm (atrial fibrillation, ventricular arrhythmia, ventricular tachycardia), valvular heart disease, acute myocardial infarction]; having the following conditions: type 1 and 2 diabetes, cardiac pacemaker, personal or family history of venous thrombosis or pulmonary embolism, presence of stroke sequelae; being an alcoholic, user of tobacco, nicotine products and illicit drugs; regularly use immunosuppressive drugs, corticosteroids, vasodilators, anxiolytics, beta-blockers and insulin; women with regular use of contraceptives or hormone replacement; and, menopausal women.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
We expect to verify that the indices of cardiovascular autonomic modulation in the experimental condition of alternating between sitting and standing in the sit-stand table will show higher activation of the sympathetic branch of the cardiac and vascular autonomic nervous system (ANS) compared to the sitting condition. Furthermore, we expect Baroreflex Sensitivity (BRS) to be increased in the sitting condition since this variable is influenced by sympathetic modulation of the ANS.

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes are not expected.