Superior Trunk Block Catheter Versus Single-shot Superior Trunk Block With Intravenous Dexmedetomidine for Shoulder Arthroplasty

Not Applicable

Completed

• Conditions: Postoperative Pain; Shoulder Arthroplasty
• Interventions: Procedure: Single-shot superior trunk block with intravenous dexmedetomidine; Procedure: Continuous superior trunk block

• Registration Number: NCT05020821
• Lead Sponsor: Yonsei University

Brief Summary

Shoulder arthroplasty is associated with significant postoperative pain. Appropriate pain control after shoulder arthroplasty is crucial for postoperative rehabilitation and patient satisfaction. Superior trunk block is a commonly employed regional anesthetic technique for shouler arthroplasty, and a continuous catheter is often placed to extend the analgesic benefit of the block. However, continuous peripheral nervel block (PNB) is more costly and time-consuming than sigle-shot PNB. Recent evidence suggests that intravenous (IV) dexmedetomidine (DEX) prolong the analgesic duration after sigle-shot PNB. The investigators will compare continuous superior trunk block with single-shot superior trunk block with IV DEX in patients undergoing shoulder arthroplasty.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-08-18
• Study First Submitted QC: 2021-08-18
• Study First Posted: 2021-08-25
• Study Start: 2021-09-02
• Primary Completion: 2022-08-09
• Study Completion: 2022-08-10
• Status Verified: 2023-10
• Last Update Submitted: 2023-10-25
• Last Update Posted: 2023-10-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

1 Patients aged 19 years old or older, with American Society of Anesthesiologists Physical Status 1-3, and scheduled for elective shoulder arthroplasty

Exclusion Criteria

1. Allergy or intolerance to any of the drugs used in the study
2. Heart failure
3. Hepatic or renal insufficiency
4. Opioid dependency
5. Coagulopathy
6. Pre-existing neurologic or anatomic deficits in the upper extremities
7. Severe psychiatric illness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Single-shot superior trunk block with intravenous dexmedetomidine	Single-shot superior trunk block with intravenous dexmedetomidine	participants receiving single-shot superior trunk block with intravenous dexmedetomidine
Continuous superior trunk block	Continuous superior trunk block	participants receiving continuous superior trunk block

Primary Outcome Measures

Name	Time	Method
Numeric rating scale pain score	24 hours after the end of surgery	Pain intensity at rest will be evaluated by an 11-point numeric rating scale (NRS: 0 = no pain, 10 = worst imaginable pain) 24 hours after the surgery.

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of