IRCT20201107049296N2招募中2 期
Evaluation of the effect of oral L-Carnitine on liver enzymes in children diagnosed with ALL in the maintenance phase of therapy: A randomized clinical trial
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 98
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 5 years 至 18 years（—）
- 性别
- All
入选标准
- •Children with acute lymphoblastic leukemia (ALL)
- •Age between 5 and 18 years
- •In maintenance phase of chemotherapy (under treatment with methotrexate and 6-mercaptopurine)
- •The serum level of liver enzymes between two and a half to ten times normal
- •Total bilirubin between 1.5 and 3 mg/dL
- •Gamma glutamyl transferase (GGT) serum level greater than or equal to 60
- •Parental informed consent to participate in the trial
排除标准
- •Having viral hepatitis, including A, B and C
- •Active infection with any of the Epstein-Barr viruses, Cytomegalovirus, herpes simplex
- •Active bacterial infection
- •Any type of underlying liver dysfunction
- •Renal dysfunction is defined by a creatinine number higher than 2 times the upper normal level
- •Taking aspirin
- •Contracting AIDS
- •Current Hypothyroidism
- •History of epilepsy
- •Sickle cell anemia
- •Suffering from malabsorption disorders
研究者
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