Acne and Mood: Impact of Treatment on Depression, Anxiety, and Sexual Function
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Percent correlation between spironolactone use for acne vulgaris and increased prevalence of sexual dysfunction.
研究概览
简要总结
This study seeks to examine if there is any relationship between spironolactone use prescribed for acne vulgaris and depression, anxiety, and/or sexual function.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female subjects between 18 and 65 years of age currently taking spironolactone for a diagnosis of acne vulgaris
- •Female subjects between 18 and 65 years of age currently taking oral antibiotics for a diagnosis of acne vulgaris
- •AND Subjects able to complete an online survey in English
排除标准
- •Subjects less than 18 years of age or older than 65 years of age Subjects that have ever been diagnosed with any mood disorder by a clinician prior to starting spironolactone (history of mood disorder or current mood disorder) Subjects taking hormonal contraception (including but not limited to oral contraceptive pills) for a duration of less than 6 months Subjects that have ever been diagnosed with any type of sexual dysfunction prior to starting spironolactone Subjects not able to complete an online survey in English Subjects taking oral isotretinoin for a diagnosis of acne Subjects that are currently pregnant
结局指标
主要结局
Percent correlation between spironolactone use for acne vulgaris and increased prevalence of sexual dysfunction.
时间窗: four weeks
Score for depression from subject reported Female Sexual Function Index (FSFI) survey.
Percent correlation between spironolactone use for acne vulgaris and increased prevalence of depression.
时间窗: one week
Score for depression from subject reported Dermatology Life Quality Index (DLQI) survey
Percent correlation between spironolactone use for acne vulgaris and increased prevalence of anxiety.
时间窗: two weeks
Score for depression from subject reported Generalized Anxiety Disorder (GAD-7) survey
次要结局
未报告次要终点
研究者
Stephanie Rangel
Research Assistant Professor of Dermatology
Northwestern University