A clinical study to see effect of two different inhalation agents (Sevoflurane vs Desflurane) on blood oxygen levels during ventilation of single lung in cancer patients.
- Conditions
- Health Condition 1: C159- Malignant neoplasm of esophagus, unspecifiedHealth Condition 2: C399- Malignant neoplasm of lower respiratory tract, part unspecifiedHealth Condition 3: C383- Malignant neoplasm of mediastinum,part unspecifiedHealth Condition 4: C768- Malignant neoplasm of other specified ill-defined sitesHealth Condition 5: C349- Malignant neoplasm of unspecifiedpart of bronchus or lungHealth Condition 6: C390- Malignant neoplasm of upper respiratory tract, part unspecified
- Registration Number
- CTRI/2020/08/027384
- Lead Sponsor
- Dr BRAIRCH AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Age of 18 years or older, but less than 70 years.
2.ASA Status I to III.
3.Patients undergoing surgeries requiring One Lung Ventilation.
4.Agree to participate in the study and have signed written informed consent.
1.Symptomatic or Severe Obstructive or Restrictive Lung disease.
Accepted definition for obstructive disease as defined by the American Thoracic Society and European Respiratory Society Guidelines is FEV1/FVC <0.7. Severity defined as FEV1/FVC <0.5 predicted as severe disease.
2.Requirement of preoperative oxygen support.
3.Preoperative intubation state or under mechanical ventilator support.
4.Baseline arterial pressure of oxygen (Pao2) <70 mm of Hg
5.Symptomatic coronary or peripheral arterial disease
6.Allergic to any drug used during the study.
7.Patients preoperatively on drugs that directly affect Hypoxic pulmonary vasoconstriction (HPV).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method