Effect of Pilates Exercise Versus Circuit Exercise Training on Gestational Hypertension
- Conditions
- Gestational Hypertension
- Interventions
- Drug: Anti-hypertensive drug (Methyldopa 250 mg)Other: Pilates exerciseOther: Circuit exercise training
- Registration Number
- NCT06618521
- Lead Sponsor
- Cairo University
- Brief Summary
The purpose of the study is to investigate the effect of Pilates exercises versus circuit exercise training on blood pressure and lipids in gestational hypertensive women.
- Detailed Description
Gestational hypertension is one of the most common disorders seen in human pregnancies. The disorder progresses into pre-eclampsia, a dangerous condition that can prove fatal to expectant mothers. If it is untreated several complications result such as eclampsia, stroke, the need for labor induction and placental abruption, preterm delivery, and low birth weight.
Most pregnant women use medication during pregnancy despite increasing availability of information about teratogenic risks. Medication use during pregnancy still causes uncertainty and concern among pregnant women and their health care providers. Medication use has a harmful effect on the fetus such as congenital anomalies, preterm birth, low birth weight, growth retardation of the fetus, and developmental delays in totality. It remains unknown what the major concerns are among pregnant women regarding medication use.
Health organizations recommend lifestyle changes that include increased levels of physical activity. Also, some researchers have recommended aerobic training for 30 minutes per day that is supplemented with resistance exercise.
Pilates exercises have been showed to be safe modality for pregnant women. It showed many benefits on childbirth. It also yields a significant decrease in clinical systolic and diastolic and mean blood pressure at rest and over 24 hours, in hypertensive non-pregnant women. Pilates may be recommended as a non-drug intervention for the prevention, treatment, and control hypertension. Circuit exercise training is also a non-drug intervention may reduce systemic arterial hypertension to lower cardiovascular risk.
Due to the progressive increase in maternal estrogen with pregnancy, maternal fat deposits switch from anabolic to catabolic states to maintain appropriate development of the fetus and placenta. This switch to catabolism increases the breakdown of fat stores, which increases total cholesterol and triglyceride available for maternal and fetal utilization. Further, it is essential for a normalized maternal lipid profile to ensure healthy fetal development and pregnancy outcomes.
Therefore, this study will be conducted to provide evidence based for the effectiveness of Pilates exercise and circuit training on blood pressure and lipid profile in gestational hypertensive women for healthcare providers interested in women's health.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 69
- They will be diagnosed by obstetrician after 20 weeks' gestation as having blood pressure higher than 140/90 without any organ damage.
- Age will range from 25-35 years old .
- Body mass index (BMI) will range from 30-34.9 Kg/m².
- Cardiac problems
- Cognitive problems
- Poorly controlled hypertension
- Diabetes mellitus
- Inflammatory stage of arthritis
- Osteoporosis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Anti-hypertensive drug Anti-hypertensive drug (Methyldopa 250 mg) It consists of 23 pregnant women. They will take Anti-hypertensive drug (Methyldopa 250 mg according to physician instructions). Anti-hypertensive drug + Pilates exercise Anti-hypertensive drug (Methyldopa 250 mg) It consists of 23 pregnant women. They will be engaged in Pilates exercise for 40 minutes/day, 3 days/week, for 12 weeks, in addition to Anti-hypertensive drug (Methyldopa 250 mg according to physician instructions. Anti-hypertensive drug + Pilates exercise Pilates exercise It consists of 23 pregnant women. They will be engaged in Pilates exercise for 40 minutes/day, 3 days/week, for 12 weeks, in addition to Anti-hypertensive drug (Methyldopa 250 mg according to physician instructions. Anti-hypertensive drug + Circuit exercise training Anti-hypertensive drug (Methyldopa 250 mg) It consists of 23 pregnant women. They will be engaged in a supervised circuit training exercises for 40 minutes/ day, 3 days/week, for 12 weeks, in addition to Anti-hypertensive drug (Methyldopa 250 mg according to physician instructions. Anti-hypertensive drug + Circuit exercise training Circuit exercise training It consists of 23 pregnant women. They will be engaged in a supervised circuit training exercises for 40 minutes/ day, 3 days/week, for 12 weeks, in addition to Anti-hypertensive drug (Methyldopa 250 mg according to physician instructions.
- Primary Outcome Measures
Name Time Method Measurement of blood pressure (BP) 12 weeks Pregnant women will sit in a relaxed position with the arm at rest on a table secure the cuff around the bicep so that it cannot move but is not tight squeeze the balloon to increase the pressure watch the aneroid monitor and increase the pressure to 20-30 mm higher than usual blood pressure after inflating the cuff, place the stethoscope just inside the elbow crease under the cuff deflated the balloon and listen to the sounds, known as Korotkoff sounds, through the stethoscope note the number on the aneroid monitor when the first sound occurs, as this systolic pressure continue listening until the steady heartbeat sound stops at this point, doctor record the number from the aneroid monitor which is the diastolic pressure. The BP will be measured for each pregnant women in the three groups before and after the end of the treatment procedures by using blood pressure device.
Assessment of serum triglycerides level 12 weeks It will be assessed for each pregnant women in the three groups before and after the end of the treatment procedures.The blood samples will be collected after fasting for 9-12 hours. Participants will be asked to lie in half lying position with well supported back and arm, the antecubital area will be cleaned with alcohol. Blood sample of about 5cm will be drawn in the morning (at 8 clock) range between 7and 25 micrograms per deciliter (mcg-dl). Blood sample will be using disposable syringe and collected in sterilized tube.
Assessment of serum total cholesterol level 12 weeks It will be assessed for each pregnant women in the three groups before and after the end of the treatment procedures.The blood samples will be collected after fasting for 9-12 hours. Participants will be asked to lie in half lying position with well supported back and arm, the antecubital area will be cleaned with alcohol. Blood sample of about 5cm will be drawn in the morning (at 8 clock) range between 7and 25 micrograms per deciliter (mcg-dl). Blood sample will be using disposable syringe and collected in sterilized tube.
Assessment of serum low-density lipoprotein (LDL) level 12 weeks It will be assessed for each pregnant women in the three groups before and after the end of the treatment procedures.The blood samples will be collected after fasting for 9-12 hours. Participants will be asked to lie in half lying position with well supported back and arm, the antecubital area will be cleaned with alcohol. Blood sample of about 5cm will be drawn in the morning (at 8 clock) range between 7and 25 micrograms per deciliter (mcg-dl). Blood sample will be using disposable syringe and collected in sterilized tube.
Assessment of serum high-density lipoprotein (HDL) level 12 weeks It will be assessed for each pregnant women in the three groups before and after the end of the treatment procedures.The blood samples will be collected after fasting for 9-12 hours. Participants will be asked to lie in half lying position with well supported back and arm, the antecubital area will be cleaned with alcohol. Blood sample of about 5cm will be drawn in the morning (at 8 clock) range between 7and 25 micrograms per deciliter (mcg-dl). Blood sample will be using disposable syringe and collected in sterilized tube.
- Secondary Outcome Measures
Name Time Method Assessment of level of stress and anxiety 12 weeks Visual analogue scale (VAS) will be used to assess the level of stress and anxiety for each pregnant woman in the three groups. VAS is a straight line; its ends are defined as the extreme limits of stress, with 0 indicates no stress and anxiety, while 10 indicates maximum stress and anxiety. The pregnant woman will select and marks on the line the suitable description of her stress level before and after the end of the treatment course.
Assessment of serum cortisol level 12 weeks It will be assessed for each pregnant women in the three groups before and after the end of the treatment procedures.The blood samples will be collected after fasting for 9-12 hours. Participants will be asked to lie in half lying position with well supported back and arm, the antecubital area will be cleaned with alcohol. Blood sample of about 5cm will be drawn in the morning (at 8 clock) range between 7and 25 micrograms per deciliter (mcg-dl). Blood sample will be using disposable syringe and collected in sterilized tube.
Trial Locations
- Locations (1)
Cairo University
🇪🇬Giza, Egypt