Head Repositioning Accuracy During Experimental Neck Pain

Not Applicable

Completed

• Conditions: Healthy; Neck Pain
• Interventions: Drug: Injection of Isotonic saline; Drug: Injection of hypertonic saline

• Registration Number: NCT04001218
• Lead Sponsor: Aalborg University

Brief Summary

This study investigates if/how an experimentally applied neck muscle pain influences head repositioning error in healthy participants.

Detailed Description

Healthy volunteers will participate in a single session study with a crossover design.

During the study healthy participants will be randomized to either receive a injection of hypertonic saline (painful injection) or isotonic saline (control injection) in a neck muscle.

Head repositioning accuracy will be assessed with and without performing a cognitive task.

Study Timeline

• Study Start: 2015-04-09
• Primary Completion: 2015-09-22
• Study Completion: 2015-09-22
• Status Verified: 2019-06
• Study First Submitted: 2019-06-26
• Study First Submitted QC: 2019-06-27
• Last Update Submitted: 2019-06-27
• Study First Posted: 2019-06-28
• Last Update Posted: 2019-06-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

• Healthy men and women aged 18-50 years
• Right handed
• Able to speak, read and understand Danish or English
• Normal pain free neck and shoulder range of motion

Exclusion Criteria

• Pain from the neck or shoulder area
• Prior surgery in neck or shoulder
• Pregnancy
• Drug addiction defined as the use of cannabis, opioids or other drugs
• Self reported neurologic, musculoskeletal or mental illnesses

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Control condition	Injection of Isotonic saline	Participants will be injected with 0.5ml Isotonic saline (0.9%) into a neck muscle
Painful condition	Injection of hypertonic saline	Participants will be injected with 0.5ml hypertonic saline (5.8%) into a neck muscle

Primary Outcome Measures

Name	Time	Method
Change in head repositioning accuracy	Within session (session lasts approximately 2 hours)	Participants will be blindfolded and asked asked to, from a neutral position, to move the head into full range of motion before returning to to a neutral position again. The difference between the start and end position will be used as an estimate of head repositioning error.

Secondary Outcome Measures

Name	Time	Method
Change in perceived pain	Within session (session lasts approximately 2 hours)	Pain will be scored using a scale from 0-10 with 0 being no pain and 10 being worst imaginable pain, by drawing on body charts and choosing words from the McGill Pain Questionnaire.
Change in perceived performance of head repositioning accuracy test	Within session (session lasts approximately 2 hours)	Likert scores of the perceived difficultness (0=no problems, 1=minimally difficult, 2=somewhat difficult, 3=fairly difficult, 4= very difficult, 5=unable to perform)

Trial Locations

Locations (1)

Dept. Of Health Science and Technology, SMI, Aalborg University; 🇩🇰 Aalborg, Denmark