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Remotely Delivered Behavioral Weight Loss Using an Ad Libitum Plant-Based Diet Versus a Balanced Calorie Deficit Diet

Not Applicable
Completed
Conditions
Obesity
Overweight
Registration Number
NCT05337150
Lead Sponsor
Drexel University
Brief Summary

This pilot randomized controlled trial will compare a remotely delivered behavioral weight loss program with a balanced calorie deficit diet (the current gold-standard) to a behavioral weight loss program with an ad libitum whole food plant-based diet (WFPBD) amongst adults with overweight/obesity (N = 52). The 6-month intervention will consist of 3 months of moderate-intensity intervention (weekly online modules and brief coaching calls), then a low-intensity period (3 calls over 3-months). Assessments will occur at baseline, 6-weeks, 12-weeks, and post-treatment (6-months). Acceptability, dietary adherence, weight, quality of life, depressive symptoms, and subjective appetite will be assessed.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
55
Inclusion Criteria
  • BMI 27-50 kg/m2
  • Ages 18-75 years
  • Resides in the U.S.
  • Consistent access to internet at home
  • Proficient skill level in speaking, writing, and understanding English
  • Reporting a desire to lose weight
  • Consistently available for 15-minute once-weekly video appointment between the hours of 8 AM and 7 PM EST
  • Willing to follow a whole food plant-based diet or a traditional calorie-reduced diet for the study duration
  • Individuals must provide consent for the research team to contact their personal physician if necessary, to provide clearance or to consult about rapid weight loss
Exclusion Criteria
  • Currently pregnant or breastfeeding or planned pregnancy within the study period
  • Recent weight loss (≥ 5% weight loss in 3-months prior to the study)
  • History of bariatric surgery
  • Currently following a low-fat plant-based diet
  • Medical condition (e.g., cancer, type I diabetes, renal failure), current substance use problem, or psychiatric condition (e.g., active substance abuse, eating disorder) that may pose a risk to the participant during intervention or cause a change in weight
  • Recently began or changed the dose of a medication that can cause significant change in weight
  • Planning on quitting cigarette smoking over the program period
  • Participation in a concurrent weight loss program during the study period
  • Medical diagnosis currently influencing weight or appetite
  • Medical condition that would limit ability to participate in this program (for example, mild stroke, diabetes if taking insulin, head trauma, cognitive disorder)
  • Acute suicidality
  • Currently meets criteria for regular loss-of-control eating (i.e., ≥ 9 binge episodes in past 3 months
  • Currently reports engaging in a compensatory behavior

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Weight ChangeMeasured at each assessment baseline, mid-treatment (6- and 12-weeks) and post-treatment (6-months).

Weight loss will be self-reported by participants using a standardized weighing procedure. Participants will weigh themselves in lightweight clothes without shoes with a digital scale accurate to 0.1 kg. Percent weight loss at 6-months will be calculated as the percentage loss in initial body weight at baseline by the time of the post-treatment assessment.

Secondary Outcome Measures
NameTimeMethod
Subjective Appetite as assessed by visual analogue scale (VAS)Measured at baseline, mid-treatment (6- and 12-weeks) and post-treatment (6-months).

Subjective appetite will be assessed using 6 visual analogue scale items (VAS) inquiring about past-week hunger, fullness, the degree to which hunger made it difficult to follow the prescribed diet, preoccupation with thoughts of food, and being bothered by hunger on a visual analogue scale of 0-100. Scores on the fullness item will be reversed, such that higher scores will indicate greater subjective appetite.

Trial Locations

Locations (1)

Drexel University

🇺🇸

Philadelphia, Pennsylvania, United States

Drexel University
🇺🇸Philadelphia, Pennsylvania, United States
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