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临床试验/NCT01852227
NCT01852227已完成不适用

ADAPT A Direct Aspiration, First Pass Technique for the Endovascular Treatment of Stroke

Medical University of South Carolina1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2013年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
500
试验地点
1
主要终点
Discharge national institutes of health stroke scale (NIHSS)

研究概览

简要总结

In collaboration with the Neurointerventional programs at state university of new york Buffalo, state university of new york Stonybrook, Swedish Medical Center, Erlanger Health System, Vanderbilt University, and West Virginia University School of Medicine, the investigators aim to prospectively collect experiences where direct aspiration as a first pass technique is used for thrombectomy procedures.

The investigators also want to compare specific characteristics from these cases to other stroke cases where traditional thrombectomy devices were used.

详细描述

Traditionally, at a physician's discretion, first pass attempts at thrombectomy procedures are performed with any number of FDA cleared catheters, guide wires, and devices designed for efficient removal of clot within an intracranial vessel. Among institutions involved in this case study, the latest devices are readily available and fully support standard treatment paradigms.

However, several cases, recently completed, using only large bore catheter and aspiration have anecdotally demonstrated a superior ability to remove clot from vessels, restoring blood flow to the affected vessel and brain tissue. In these limited number of cases, full restoration of blood flow has been achieved. While this combination of approved devices is minimalistic, the efficiency of the procedure, rapid technical success, and relative simplicity of the approach is unique and should be thoroughly reviewed and possibly prepared for publication.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • All patients who were treated with direct aspiration as a first pass choice or treated with a stent retriever will be included.

排除标准

  • Patients not treated with either direct aspiration as a first pass, or stent retriever will not be included.

结局指标

主要结局

Discharge national institutes of health stroke scale (NIHSS)

时间窗: approximately 7 days after index stroke

a national institutes of health stroke scale (NIHSS) will be obtained at the time of the each patient's discharge or approximately 7 days

次要结局

  • 90 day modified Rankin Score (mRS)(90 days after procedure)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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