Effect of probiotic supplementation in treatment of children with attention deficit hyperactivity disorder

Not Applicable

Conditions: Attention Deficit Hyperactivity Disorder.
Disturbance of activity and attention

Registration Number: IRCT2017090133941N16

Lead Sponsor: Vice chancellor for research, Kashan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 40

Inclusion Criteria

Children aged between 8 and 12 years
Patients diagnosed with attention deficit hyperactivity disorder based on DSM-IV criteria

Exclusion Criteria

mental disorders
bipolar disorder
pervasive developmental disorders
autism
not interested to be in research
consuming probiotic yogurt, kefir and other fermented foods
taking probiotic, antioxidant and/or anti-inflammatory supplements including vitamin E, vitamin C and omega-3 fatty acid
taking antibiotics

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ADHD rating scale. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Questionnaire.

Secondary Outcome Measures

Name	Time	Method
Hs-CRP. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Elisa kit.;Nitric oxide. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Spectrophotometry.;Malondialdehyde. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Spectrophotometry.;Glutathione. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Spectrophotometry.;Total antioxidant capacity. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Spectrophotometry.;Hamilton Anxiety Rating scale. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Questionnaire.;Depression. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Questionnaire.