EUCTR2011-000571-13-DK进行中（未招募）不适用
The effect of GLP-1 in psoriasis
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Caucasians above 18 years of age
- •Plaque psoriasis
- •PASI score >10
- •No treatment or stable treatment of psoriasis during at least 3 months before inclusion
- •Steady weight through 3 months with a body mass index (BMI) of maximum 30kg/m2
- •Normal blood pressure
- •Spiral or hormonal birth control
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Psoriasis arthritis
- •Fasting plasma glucose > 7.5 mmol/L
- •Type 1 diabetes
- •Type 2 diabetes
- •Treatment for type 2 diabetes with GLP-1-based medicine (DDP-4-inhibitors or GLP-1-receptor-agonists)
- •Heart failure, NYHA class III-IV
- •Uraemia, end-stage renal disease, or any other cause of impaired renal function with s-creatinine >150 µM and/or albuminuria
- •Liver disease (alanine amino transferase (ALAT) and/or aspartate amino transferase (ASAT) >2 x upper normal serum levels)
- •Screening calcitonin >50ng/L
- •Acute or chronic pancreatitis
- •Struma or thyroid cancer
- •Pregnancy or breast feeding
- •Inability to complete the study
研究者
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