The Effect of Combined Popliteal and Saphenous Block in Addition to General Anesthesia in Surgical Fixation of Ankle Fractures: a Prospective Randomized Study
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 主要终点
- Use of Morphine
研究概览
简要总结
This clinical, randomized, and controlled study will provide valuable scientific evidence regarding the effect of adding peripheral nerve blockades to general anaesthesia during ankle surgery. In particular, the investigators want to determine if the need for postoperative opioids will be reduced and whether this will lead to shorter admission to recovery room and fewer instances of side effects such as postoperative nausea and vomiting. In addition, the investigators will determine whether the functional outcome is improved i.e. faster and more successful rehabilitation. This would have profound benefits not only to the individual patient but also to society by reducing expenses during admission, the cost of sick leave etc.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >18 years
- •Patients in need of anaesthesia for operative fixation of ankle fractures.
- •American Society of Anesthesiologists (ASA) score 1-
- •BMI > 18 og <
- •Oral and written consent
排除标准
- •Weight < 50kg
- •Allergy towards drugs used in the study
- •Patients for re-operation
- •Other fracture at the same time
- •Pregnancy
- •Daily use of opioids within two weeks before operation
- •Infection near the application site
- •Patients in need of dialysis
- •Patients with neuropathy in lower extremities
研究组 & 干预措施
Block
Popliteal and saphenous Block with Ropivacaine
干预措施: Ropivacaine block (Drug)
NaCl
干预措施: Ropivacaine block (Drug)
结局指标
主要结局
Use of Morphine
时间窗: 24 hours
次要结局
- Functional rehabilitation outcome(10-14 weeks)
研究者
Heidi Kruse
Pregraduat research assistent
Herlev Hospital
