Six dial mechanical ventilation strategy versus self inflating adult bag valve ventilation in adult cardiac arrest patients undergoing chest compressions- A Randomized Crossover Non-Inferiority trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To compare the efficacy of mechanical ventilator with self inflating adult bag valve ventilation in delivery of tidal volume during cardiopulmonary resuscitation (CPR) in Emergency medicine department.
研究概览
简要总结
The American Heart Association estimates that approximately 1000 cardiac arrests occur each day. The American Heart Association updated its recommendations in 2020 and suggested that a tidal volume of approximately 500 to 600 ml, sufficient to cause a visible chest rise, provides adequate ventilation while minimising the risk of overdistension or gastric inflation. Airway management and ventilation during CPR are essential for successful resuscitation in these patients. Studies have compared mechanical ventilation with bag-valve ventilation for gas exchange and have shown that mechanical ventilation is at least feasible and safe for use during CPR in intubated cardiac arrest patients. Another study, using a physical model during simulated cardiopulmonary resuscitation, found that conventional ventilation modes during simulated CPR manoeuvres produced pressures and volumes similar to those reported with bag-valve masks. Studies have yet to be conducted to determine the efficacy of tidal-volume delivery via mechanical ventilation and bag-valve ventilation in cardiac arrest patients. This study will evaluate the efficacy of tidal volume delivery during mechanical ventilation versus bag-valve ventilation in adult intubated cardiac arrest patients undergoing cardiopulmonary resuscitation in the emergency medicine department.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)(—)
- 性别
- All
入选标准
- •Intubated adult cardiac arrest patients undergoing cardiopulmonary resuscitation in the emergency department and meeting the termination of resuscitation criteria.
排除标准
- •1.Age less than 18 years .
- •2.Pregnant women.
- •3.Bleeding or secretions in the endotracheal tube.
结局指标
主要结局
To compare the efficacy of mechanical ventilator with self inflating adult bag valve ventilation in delivery of tidal volume during cardiopulmonary resuscitation (CPR) in Emergency medicine department.
时间窗: 5 minutes
次要结局
- To compare ET CO2 levels on ventilation with mechanical ventilator and bag-valve ventilation.(5 minutes)
- To compare expiratory tidal volume on ventilation with mechanical ventilator and Bag valve ventilation(5 minutes)
研究者
S Vinay
Jawaharlal institute of postgraduate medical education and research
