跳至主要内容
临床试验/CTRI/2026/03/106880
CTRI/2026/03/106880尚未招募不适用

Effect of a Modified Respiratory Rehabilitation Program on Exercise-Induced Forced Expiratory Volume for 1 second Decline in Long-Distance Runners with Exercise-Induced Bronchospasm: A Randomized Controlled Trial

未提供1 个研究点 分布在 1 个国家目标入组 62 人开始时间: 2026年11月9日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
尚未招募
入组人数
62
试验地点
1
主要终点
decline percentage of forced expiratory volume for 1 second

研究概览

简要总结

This randomized controlled trial evaluates the effectiveness of a 5-week Modified Respiratory Rehabilitation Program compared to standard aerobic exercise in improving lung function and exercise tolerance in long-distance runners with Exercise-Induced Bronchospasm. The study targets 146 participants aged 18-45 years who are actively training long-distance runners experiencing at least 10 percent decline in Forced Expiratory Volume in 1 second after exercise challenge. Participants will be randomly assigned to either the intervention group receiving Modified Respiratory Rehabilitation, including High-Intensity Interval Respiratory Training, breathing pattern optimization, and sport-specific running protocols, or the control group receiving standard aerobic exercise training. Both groups will undergo supervised 5-week programs conducted by qualified physiotherapists. The primary outcome is the post-exercise FEV1 decline percentage. Secondary outcomes include inspiratory and expiratory muscle strength, exercise tolerance measured by VO2 Max, and health-related quality of life using the SF-36 questionnaire. Assessments will be conducted at baseline and after 5 weeks of intervention. The study aims to provide evidence for non-pharmacological management of Exercise-Induced Bronchospasm in competitive athletes, offering an alternative approach that aligns with anti-doping regulations and holistic training preferences. This research addresses a significant gap in respiratory rehabilitation applications for athletes with exercise-induced airway narrowing and may inform clinical guidelines for this population.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 45.00 Year(s)(—)
性别
All

入选标准

  • Age 18–45 years.
  • On screening, confirmed EIB FEV 1 decline of more than 10 percent Actively training long-distance runners more than 40 km per week No chronic respiratory conditions Willing to complete 5 week intervention and assessments.

排除标准

  • Recent respiratory infection (more than 4 weeks).
  • Significant comorbidities (e.g., cardiovascular disease, diabetes mellitus asthma ).
  • Participation in conflicting clinical trials.
  • Pregnancy or lactation.

结局指标

主要结局

decline percentage of forced expiratory volume for 1 second

时间窗: decline percentage of forced expiratory volume for 1 second

次要结局

  • IMP(EMP)

研究者

发起方
未提供
责任方
Principal Investigator
主要研究者

vishagh kumar v nair

Bharati Vidyapeeth (DU) School of Physiotherapy, Sangli

研究点 (1)

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