A Study to Evaluate if Siddha Medicine Can help reduce Weight and Body Measurements in People with Moderate Obesity Over 90 Days

Phase 2/3

Not yet recruiting

• Conditions: Obesity, unspecified,

• Registration Number: CTRI/2025/06/088766
• Lead Sponsor: National Institute of Siddha

Brief Summary

This open labelled single centric randomized prospective clinical trial to evaluate the therapeutic efficacy of a Siddha regimen Thiripala Chooranam Nerunjil kudineer and Jalamanjari Chenduram for 90 days at Ayothidoss Pandithar hospital chennai in managing class 1 and 2 obesity participants aged 18-60 years with bmi  greater than or equal to 30 kg per meter square will be randomized into two groups

group 1 siddha regimen only and group two siddha regimen with low calorie diet the primary objective is to achieve a 5 to 10 percent reduction in bmi and anthropometric measurements while secondary objectives include assessing changes in laboratory parameters and quality of life the study includes known case of diabetes mellitus obesity bmi greater than or equal to 30 kg per meter square obesity class one bmi 30 to 34.9 kg per meter square obesity class two bmi 35 to 39.9 kg per meter square and excludes vulnerable groups hypothyroidism and malignancy aiming to provide evidence on the efficacy of siddha medicine in obesity management

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-05-23
• Study Start: 2025-06-26

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

K/C/O Diabetes Mellitus Obesity-BMI greater than or equal to 30kg/m^2 Obesity class l-BMI 30 to 34.9kg/m^2 Obesity class ll-BMI 35 to 39.9kg/m^2.

Exclusion Criteria

Vulnerable groups (Pregnancy and lactation) Hypothyroidism Malignancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
A 5 to 10 percent reduction in BMI and a reduction in anthropometric measurements	90 days
from baseline to endpoint.	90 days

Secondary Outcome Measures

Name	Time	Method
To assess the difference in laboratory parameters and Enhanced Quality of Life from	baseline to endpoint

Trial Locations

Locations (1)

Ayothidoss Pandithar Hospital; 🇮🇳 Chennai, TAMIL NADU, India

Ayothidoss Pandithar Hospital

🇮🇳Chennai, TAMIL NADU, India

Dr S MANJUSREE

Principal investigator

9677875915

manjusree715@gmail.com