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Clinical Trials/CTRI/2024/01/061627
CTRI/2024/01/061627Not yet recruitingPhase 3

EFFICACY OF N-ACETYL CYSTEINE IN ANTITUBERCULAR DRUG INDUCED HEPATOTOXICITY – A RANDOMISED CONTROL STUDY - NI

AIIMS jodhpur0 sites0 target enrollmentStarted: TBDLast updated:
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Trial Snapshot

Phase
Phase 3
Status
Not yet recruiting
Study OverviewEligibility CriteriaInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional

Eligibility Criteria

Inclusion Criteria

  • •Patient diagnosed with antitubercular drug induced hepatotoxicity.
  • •Patients Age >18 year of either sex and meet the all / any of the following criteria:
  • •(i) a rise of five times the upper limit of normal levels of serum AST and/or ALT
  • •without symptom of hepatotoxicity.
  • •(ii) a rise of two times the upper limit of normal level of serum bilirubin.
  • •(iii) More than 3 times increase in AST and/or ALT levels together with the hepatitis

Exclusion Criteria

  • •1.History of alcoholism and known case of alcoholic liver disease.
  • •2. Known case of HIV, HBV, HCV.
  • •3. Liver injury due to drugs other than ATT.
  • •4. Pregnant or breastfeeding women.

Investigators

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