ALI in Cancer Patients

Not yet recruiting

• Conditions: Acute Limb Ischemia

• Registration Number: NCT06882187
• Lead Sponsor: Assiut University

Brief Summary

The aim of the study is to describe and evaluate the outcomes of cancer patients presenting with and treated for ALI at our center .

Detailed Description

Acute limb ischemia (ALI) is a vascular emergency and is associated with significant morbidity and mortality. Peripheral arterial embolism or thrombosis from malignant disease is uncommon and a rare cause of acute limb ischemia. Limb ischemia can be caused by emboli from the tumor itself, from metastatic deposits within large vessels, as well as the tumors of adjacent organs such as the lung, which invade the left or right atrium of the heart and then disseminate to the main arteries of the body. This acute event may be the first indication of malignant disease in the patient.

Study Timeline

• Status Verified: 2025-03
• Study First Submitted: 2025-03-12
• Study First Submitted QC: 2025-03-12
• Last Update Submitted: 2025-03-12
• Study First Posted: 2025-03-18
• Last Update Posted: 2025-03-18
• Study Start: 2025-05-01
• Primary Completion: 2026-05-01
• Study Completion: 2026-07-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• All cancer patient presented to Vascular and Endovascular surgery departement with ALI.

Exclusion Criteria

• Patients with benign tumors or without active malignancy.
• Patients with iatrogenic limb ischemia related to a tumor chemoembolization procedure.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Limb Salvage	baseline