The Improvement of ovarian cortex survival by supplementation of Growth Hormone (GH) in freezing media.
Phase 1
Recruiting
- Conditions
- The effect of growth hormone added in vitrification solution for preserve the human ovarian tissue.growth hormone,anti-apoptotic agent,ovarian tissue,vitrification
- Registration Number
- TCTR20170324002
- Lead Sponsor
- The Factory of Medicine, Prince of Songkla University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 20
Inclusion Criteria
1 The patient has a benign ovarian cyst confirmed with ultrasound and the treatment plan is to undergo a unilateral oophorectomy or bilateral oophorectomy by laparotomy or laparoscopy between 25 Januaray to 30 March 2017
2 Informed consent by the patient
Exclusion Criteria
1 During the operation the cyst looked malignant or suggested malignant from frozen section
2 The surgeon considered that for the benefit of the patient the surgery should be converted from oophorectomy to cystectomy only
3 The ovarian cortex retrieved is not appropriate for the size of 2 x 2 x 0 1 cm which may be caused by the size of the cyst
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of intact follicles following ovarian tissue vitrification . 7-14 days after freezing H&E with light microscopy.
- Secondary Outcome Measures
Name Time Method Percentage of intact follicles following ovarian tissue vitrification . 7-14 days after freezing Transmission electron microscopy.