A phase II trial to investigate the safety of early high dose methylprednisolone in acute leprous neuritis and leprosy type 1 reactions with neuritis in Nepal

Phase 2

Completed

• Conditions: eprosy; Infections and Infestations; Leprosy

• Registration Number: ISRCTN31894035
• Lead Sponsor: ondon School of Hygiene and Tropical Medicine (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-04-04
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Those with type 1 reaction with new nerve function impairment
2. Age 16-65 years

Exclusion Criteria

1. Type 1 reaction without new nerve function impairment
2. Systemic corticosteroids in the preceding three months
3. Contraindications to steroids
4. Pregnancy
5. Severe active infection
6. Severe intercurrent illness

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
erve function

Secondary Outcome Measures

Name	Time	Method
Amount of additional steroid required