Comparison of the Effect of Transcutaneous Auricular Vagus and Trigeminal Nerve Stimulation on Heart Rate Variability
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Autonomic Nervous System Imbalance
- Sponsor
- Bahçeşehir University
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Heart Rate Variability
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The aim of this study was to compare the results between transcutaneous auricular vagus nerve stimulation and trigeminal nerve stimulation with the results obtained from heart rate variability, pulse and blood pressure measurements and to reveal which method is more effective in autonomic nervous system neuromodulation.
Hypotheses of the study:
H0: Vagus nerve stimulation is more effective than trigeminal nerve simulation in terms of heart rate variability.
H1: Trigeminal nerve stimulation is more effective than vagus nerve simulation in terms of heart rate variability.
Detailed Description
In this study, 80 healthy participants (40 males, 40 females) aged between 20-50 years were randomized (www.randomizer.org) into four groups by computer software. After randomisation, one group was received transcutaneous vagus nerve stimulation inside the ear, while the other group was received trigeminal nerve stimulation above the ear.The third group received sham transcutaneous vagus nerve stimulation and the fourth group received sham trigeminal nerve simulation. Heart rate variability, pulse rate and blood pressure measurements were performed to determine which stimulation method is more effective. Heart rate variability was analysed with Kubios HRV programme after the 5-minute short measurement method. SNS, PNS and Stress Index and LF, HF and LF/HF parameters were evaluated in heart rate variability sub-parameters.
Investigators
Alper Percin
Asst. Prof.
Bahçeşehir University
Eligibility Criteria
Inclusion Criteria
- •To be 18 years of age or older,
- •Not having any acute or chronic disease.
Exclusion Criteria
- •Having any acute or chronic disease,
- •Having previously undergone vagus nerve stimulation or trigeminal nerve stimulation.
Outcomes
Primary Outcomes
Heart Rate Variability
Time Frame: Pre-intervention and immediately after the intervention
5 minutes of heart rate variability was measured.
Secondary Outcomes
- Systolic and Diastolic Blood Pressure(Pre-intervention and immediately after the intervention)