to know the effect of diet/ exercise and metformin in patients with boarderline high sugar levels
Phase 4
Completed
- Conditions
- Health Condition 1: E139- Other specified diabetes mellituswithout complicationsHealth Condition 2: null- prediabetes
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 105
Inclusion Criteria
body mass index 18.5-29.9Kg/m2
Non diabetic individuals with either impaired fasting glucose (FBS >100mg/dl < 126mg/dl), impaired glucose tolerance (2hr glucose PPBS >140 <200mg/dl), Hb A1c 5.7% -6.4%
Exclusion Criteria
1.Diabetic patients Type 1 and 2 (FBS >126mg/dl, PPBS >200mg/dl and HbA1c >6.5%)
2.Patients with contraindications to Metformin (CCF, hepatic dysfunction, renal impairment) and hypersensitivity
3.Pregnant and lactating women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method At the end of 1 year the patient will be categorized as mentioned below based on the findings. <br/ ><br>Normal â?? FBS 100mg/dl, 2hr glucose PPBS140mg/dl and HbA1c 5.6% <br/ ><br>Prediabetic- FBS 100mg/dl 126mg/dl) or 2hr glucose PPBS 140 200mg/dl <br/ ><br>or HbA1c 5.7% -6.4% <br/ ><br>Diabetic â??FBS126mg/dl or 2hr glucose PPBS 200mg/dl and HbA1c 6.5% <br/ ><br>Timepoint: At the end of 1 year the patient will be categorized as mentioned below based on the findings. <br/ ><br>Normal â?? FBS 100mg/dl, 2hr glucose PPBS140mg/dl and HbA1c 5.6% <br/ ><br>Prediabetic- FBS 100mg/dl 126mg/dl) or 2hr glucose PPBS 140 200mg/dl <br/ ><br>or HbA1c 5.7% -6.4% <br/ ><br>Diabetic â??FBS126mg/dl or 2hr glucose PPBS 200mg/dl and HbA1c 6.5% <br/ ><br>Recruitment has started in the month of september 2016 and follow up is after 3 months , 6 months and 1 year <br/ ><br>
- Secondary Outcome Measures
Name Time Method antioxidants in prediabetic subjectsTimepoint: one year