NCT01442701已完成不适用
Stanford's Outcomes Research in Kids (STORK)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 361
- 试验地点
- 1
- 主要终点
- Height-for-weight Z scores
研究概览
简要总结
The investigators intend to investigate whether the rise in childhood obesity is caused by the loss of recurrent and chronic infections in modern, industrialized society, beginning in utero and extending through early childhood. The investigators will also examine whether the antimicrobial triclosan, present in numerous cleaning and hygiene products, decreases the incidence of infection within a household.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Subjects must meet all of the following inclusion criteria to participate in the study:
- •Able to provide written informed consent.
- •Able to communicate effectively in verbal English or Spanish.
- •Willing to provide blood, saliva, urine and stool specimens from herself, and willing to provide blood, saliva, urine and stool specimens from her infant.
- •Willing to provide consent for review of Primary Provider Medical Records regarding, for the mother, medical history and infectious and other conditions during pregnancy, and for the infant, Apgar scores, height and weight measurements at birth and over time, infectious and other disease diagnoses and treatment, and vaccination records.
排除标准
- •More than one fetus.
- •High risk pregnancy.
- •Intent to move from the Bay Area within three years after enrollment.
- •History of diagnosis and/or treatment, and any current diagnosis or treatment, of type 1 diabetes or of major mental illness.
- •History of diagnosis and/or treatment, and any current diagnosis or treatment, of a thyroid disorder or other endocrine condition.
- •History of diagnosis and/or treatment, and any current diagnosis or treatment that has resulted in severe immunosuppression.
- •A household member who has a compromised immune system
- •Other conditions that in the opinion of the PI would make the subject an unacceptable candidate for this study.
结局指标
主要结局
Height-for-weight Z scores
时间窗: Age 3 years
We will determine whether an association exists between height-for-weight Z-score (with adjustment for age and sex) and infectious disease load.
次要结局
- Cumulative sick-days(In utero to 3 years of age)
研究者
Julie Parsonnet
Professor
Stanford University
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Pacific Kids DASH for HealthOverweightBlood PressureNCT00905411Kaiser Permanente88
已完成
不适用
Factors Associated With Changes in Weight-status in Danish School Children With ObesityPediatric ObesityNCT06077266University of Aarhus467
已完成
不适用
Brain Mechanisms of Overeating in ChildrenPediatric ObesityInhibitionDecision MakingfMRINCT03341247Penn State University254
招募中
不适用
Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.ObesityNCT01998750Columbia University500
已完成
不适用
Effects of Exercise Intensity in Obese Children and AdolescentsObesityNCT01991106Norwegian University of Science and Technology100