Effect of Cinnamon on Glucose and Lipid Levels in Non-Insulin Dependent Type 2 Diabetes Mellitus
Phase 2
Completed
- Conditions
- Diabetes Mellitus, Adult Onset
- Interventions
- Registration Number
- NCT00237640
- Lead Sponsor
- University of Oklahoma
- Brief Summary
The purpose of this study is to determine the effects of cinnamon on serum glucose and lipid levels in people with non-insulin dependent type 2 diabetes mellitus.
- Detailed Description
Forty people with non-insulin dependent type 2 diabetes mellitus will be randomized to receive either cinnamon or placebo for three months. The dose of cinnamon will be one gram daily. Fasting serum glucose, triglyceride, total cholesterol, LDL, HDL, and insulin levels will be measured at baseline and at 1, 2, and 3 months. HbA1c levels will be measured at baseline and at 3 months. Patients will be monitored for compliance, adverse effects, and dietary changes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 85
Inclusion Criteria
- Type 2 diabetes mellitus
- HbA1C > 6.0%
- Age 18 and above
- Able to obtain consent
Exclusion Criteria
- Currently taking insulin
- Pregnancy
- End-stage renal disease
- Hemolytic anemia
- Cinnamon intolerance
- Inability or unwillingness to adhere to study protocol
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 Cinnamon or placebo 500 mg capsule twice daily - 2 Cinnamon or placebo 500 mg capsule twice daily -
- Primary Outcome Measures
Name Time Method - Primary outcomes include HbA1c, glucose, total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides levels. 3 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
General Clinical Research Center
🇺🇸Oklahoma City, Oklahoma, United States