Physical Parameters in Osteoarthritis Stages

Completed

• Conditions: Pain; Quality of Life; Osteoarthritis
• Interventions: Diagnostic Test: Radiographic classification

• Registration Number: NCT06015412
• Lead Sponsor: Selcuk University

Brief Summary

To investigate the extent to which pain, functionality, and quality of life change over the progression of osteoarthritis grades.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-11-01
• Primary Completion: 2023-05-01
• Study Completion: 2023-07-01
• Status Verified: 2023-08
• Study First Submitted: 2023-08-21
• Study First Submitted QC: 2023-08-23
• Last Update Submitted: 2023-08-23
• Study First Posted: 2023-08-29
• Last Update Posted: 2023-08-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 161

Inclusion Criteria

• having the same OA grade in both knees
• volunteering to participate in the study
• not having undergone previous lower extremity surgery

Exclusion Criteria

• neurological disorders;
• those with a history of surgery related to the lower extremities;
• those with orthopedic problems in the lower extremities, such as tendinopathy and bursitis;
• those who had neurological, orthopedic, or cognitive disorders that would prevent walking;
• those with a diagnosis of diabetes, obesity, or rheumatological disorders;
• those who had received intra-articular injection therapy within the last three months;
• and those with malignancy or perception problems.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Grade 2 osteoarthritis	Radiographic classification	disease stages 2 according to the Kellgren-Lawrence radiographic classification system
Grade 1 osteoarthritis	Radiographic classification	disease stages 1 according to the Kellgren-Lawrence radiographic classification system
Grade 4 osteoarthritis	Radiographic classification	disease stages 4 according to the Kellgren-Lawrence radiographic classification system
Grade 3 osteoarthritis	Radiographic classification	disease stages 3 according to the Kellgren-Lawrence radiographic classification system

Primary Outcome Measures

Name	Time	Method
Visual Analog Scale (VAS)	2 minutes	a 10-cm straight line with 0 on one end indicating no pain and 10 on the other end signifying unbearable pain. The participants were asked to mark the intensity of their current pain on the line
two-minute walk test (2MWT)	2 minutes	A 45-meter corridor was used for the 2MWT. The start and end points were marked, and the participants were asked to walk at a normal pace within these boundaries. The distance covered in two minutes was recorded
Nottingham Health Profile (NHP)	10 minutes	This tool comprises 38 questions in six domains, namely energy, pain, social isolation, physical mobility, emotional reactions, and sleep. Each domain is scored from 0 to 100. The total score is obtained by summing the scores obtained from the six domains. High scores indicate a good quality of life.
Western Ontario and McMaster Universities Osteoarthritis Index	10 minutes	The questionnaire consists of 24 items, each scored from 0 to 4. The total score is obtained by summing the point equivalents of the responses given to all items. A higher score indicates poorer functionality

Trial Locations

Locations (1)

Selcuk University; 🇹🇷 Konya, Selçuklu, Turkey