A PROSPECTIVE RANDOMISED DOUBLE BLINDED STUDY TO ASSESS THE INTUBATING CONDITIONS OF TWO NON DEPOLARISING MUSCLE RELAXANTS CISATRACURIUM AND ROCURONIUM
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Percentage depression of adductor pollicis twitch at 180 seconds
研究概览
简要总结
Title : A Prospective Randomised Double Binded Study To Compare The Intubating Conditions Of Two Non Depolarising Muscle Relaxants Cisatracurium And Rocuronium
Aim : To compare the percentage depression of adductor pollicis twitch at 180 seconds following single dose of these two nondepolarising muscle relaxants and alps other parameters like heart rate , mean arterial pressure, Copenhagen consensus conference score and rare side effects.
Methodology: After obtaining institutional ethics committee approval , patients who are fit under the inclusion criteria will be entrolled in the study and randomised into two groups. Group A will receive 0.1 mg/ Kg of Inj.Cisatracurium and Group B will receive 0.6 mg / kg of Inj.Rocuronium . The study parameters will be monitored. Statistical analysis will be done .
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Surgeries under general anaesthesia with tracheal intubation following non depolarising muscle relaxants ASA class1 ASA class 2 Elective surgery.
排除标准
- •ASA class 3 and above Chronic liver disease Chronic kidney disease Age>75 years Obesity > 30 kilograms per metre square Patients with anticipated difficult airway Patients with diseases affecting neuromuscular transmission ( myopathies).
结局指标
主要结局
Percentage depression of adductor pollicis twitch at 180 seconds
时间窗: Percentage depression of adductor pollicis twitch at 180 seconds
次要结局
- The Copenhagen consensus conference score(Heart rate)