Changes of Electrophysiology and Optical Coherence Tomography Angiography in Primary Open Angle Glaucoma After Phacoemulsification

Brief Summary

Detailed Description

* Study design: A prospective, non randomized, interventional, comparative study, control based study. * Location: Ophthalmology department, Sohag university hospital. In this prospective study, aiming to investigate Optical coherence tomography angiography and electrophysiological changes after cataract surgery in normal and patients with POAG with cataract 1 day before operation, 1 week and 3 months postoperatively. * Methodology The study will include 50 patients with primary open angle glaucoma associated with cataract and 50 patients have cataract without glaucoma. Preoperative and postoperative evaluation: All patients will be subjected to the following: * History taking including age, gender, family history, systemic diseases, previous medications or ophthalmic surgery. * Detailed ophthalmological examination including: Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA) by Snellen's fraction and converted into logarithm of the minimal angle of resolution LogMAR, refraction, keratometry, slit lamp biomicroscopy for anterior segment, IOP measurement by applanation tonometer, and posterior segment (Fundus) examination. * Examination of the angle of anterior chamber by goniolens. * OCTA disc and macula * Pattern ERG and multifocal ERG Surgical techniques: Patients will be subdivided into two groups: Group (A): normal Patients will undergo standard phacoemulsification surgery. Group (B): Patients with POAG will undergo standard phacoemulsification surgery. \* phaco technology by using (WHITESTAR SIGNATURE PRO, Abbott, USA) * OCT angiography will be done by (Optovue, Inc., Fremont, California, USA). * Electrophysiology will be done by (Roland consult Retimap, Germany)

Primary Outcomes

Secondary Outcomes

• Visual acuity and intra ocular pressure changes(before operation and 1st month, 3rd month post operative)