NCT05871034尚未招募不适用
Changes of Electrophysiology and Optical Coherence Tomography Angiography in Primary Open Angle Glaucoma After Phacoemulsification
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 主要终点
- Pattern and multifocal electroretinogram and Optical coherence tomography angiography of optic disc and macula changes after phacoemulsification in primary open angle glaucoma
研究概览
简要总结
To compare electrophysiological and Optical coherence tomography angiography of optic disc and macula changes after uneventful phacoemulsification between normal and cataractus patients with primary open angle glaucoma.
详细描述
- Study design: A prospective, non randomized, interventional, comparative study, control based study.
- Location: Ophthalmology department, Sohag university hospital. In this prospective study, aiming to investigate Optical coherence tomography angiography and electrophysiological changes after cataract surgery in normal and patients with POAG with cataract 1 day before operation, 1 week and 3 months postoperatively.
- Methodology The study will include 50 patients with primary open angle glaucoma associated with cataract and 50 patients have cataract without glaucoma.
Preoperative and postoperative evaluation:
All patients will be subjected to the following:
- History taking including age, gender, family history, systemic diseases, previous medications or ophthalmic surgery.
- Detailed ophthalmological examination including: Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA) by Snellen's fraction and converted into logarithm of the minimal angle of resolution LogMAR, refraction, keratometry, slit lamp biomicroscopy for anterior segment, IOP measurement by applanation tonometer, and posterior segment (Fundus) examination.
- Examination of the angle of anterior chamber by goniolens.
- OCTA disc and macula
- Pattern ERG and multifocal ERG
Surgical techniques:
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients aged: 45-65 years old with cataract density doesn't interfere with Pre-operative imaging (N1-N2).
- •Patients with primary open angle diagnosed for at least 2 years with glaucoma treatment associated with cataract (N1-N2).
- •Exclusion criteria:
- •s▪ patient with PACG.
- •Previous intraocular surgery.
- •Associated ocular or intra ocular inflammation
- •Previous history of eye trauma.
- •Associated intraocular pathology
排除标准
- 未提供
结局指标
主要结局
Pattern and multifocal electroretinogram and Optical coherence tomography angiography of optic disc and macula changes after phacoemulsification in primary open angle glaucoma
时间窗: before operation and 1st month, 3rd month post operative
electrophysiology and optical coherence tomography angiography changes
次要结局
- Visual acuity and intra ocular pressure changes(before operation and 1st month, 3rd month post operative)
研究者
Shorouq Abdelrahman Hassan
Assistant lecturer
Sohag University
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