Intravenous Paracetamol vs Tramadol for pain management in patients with Acute Pancreatitis
Not Applicable
- Conditions
- Pain Management in Acute Pancreatitis
- Registration Number
- JPRN-UMIN000037790
- Lead Sponsor
- ational Academy of Medical Sciences, Bir Hospital
- Brief Summary
In this study, 80 patients were enrolled and included in the final analysis. The study subjects had a mean age of 39.33 +/- 13.3 years and 62(77.5%) of them were male. Alcohol was the etiology for pancreatitis in 67.5% (n=54) of patients. Mean VAS scores at baseline and 24 hours were similar in the two groups. Similarly, the change of scores from the baseline to the 24 hours did not differ between the groups. Comparison of pain improvements failed to reveal any differences between groups
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 78
Inclusion Criteria
Not provided
Exclusion Criteria
1)Severe hepatic impairment 2)Severe renal impairment ( CrCl < 30ml/min) 3)Ongoing treatment with NSAIDs (within 24 h) 4)History of allergy to paracetamol, and/or tramadol
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of Paracetamol vs Tramadol in pain management of Acute Pancreatitis.
- Secondary Outcome Measures
Name Time Method 1)To determine number of patients with drug related adverse events in paracetamol vs tramadol arm 2)To determine causes of acute pancreatitis 3)To analyze the incidence of severity of acute pancreatitis as per the revised Atlanta Classification 4)To determine impact of two drugs on duration of hospital stay