Effect of an Aloe vera coated 3-0 silk sutures in gum surgery.

Phase 1

Active, not recruiting

Brief Summary: This is a split mouth randomzed controlled trial evaluating and comparing uncoated 3-0 silk sutures with aloe vera coated 3-0 silk sutures.

12 chronic periodontitis patients according to inclusion criteria will be recruited. all sutures will be packed in opaque envelopes and one envelope will be chosen randomly at the time of surgery. Conventional acess flap surgery will be performed in all study patients. The flaps will be sutured interdentally using direct loop sutures with one of the suture material. Postoperative instructions will be given and analgesics (ibuprofen 400 mg TDS for 5 days) will be prescribed. Antibiotics will not be prescribed. Warm water rinse will be instructed twice daily for 1 minute for 14 days. All patients will be recalled on day 7 for suture removal and analysed for satphylococcus aureus count. Healing index and VAS index will be recorded on 7th and 14th day.

Recruitment & Eligibility

Inclusion Criteria

1 Patients diagnosed with periodontitis, with good systemic health.
2 A minimum of atleast 3 teeth indicated for periodontal flap surgery ( greater than 5 mm residual probing depth after Phase I therapy) were included in the study.

Exclusion Criteria

Patients who have undergone periodontal therapy during the previous 6 months, or exhibit poor plaque control after phase I therapy.
History of any systemic disease such as diabetes mellitus, hypertension, osteoporosis, unstable or life-threatening conditions,bleeding disorder, undergoing antibiotic or other antimicrobial therapy.
Patients on drugs like aspirin, blood thinners and anticoagulant therapy 4.
Patients with history of allergy 5.
Current or former smokers 7.
Pregnant or lactating women.

Primary Outcome Measures

Name	Time	Method
1. Healing will be assessed using Healing index by Laundry et al (1988) at 7th and 14th day.	7th and 14th day after flap surgery
2. VAS scale by Johnson EW et al (2001) at 7th and 14th day.	7th and 14th day after flap surgery
3. Microbial analysis of suture at 7th day.	7th and 14th day after flap surgery

Secondary Outcome Measures

Name	Time	Method
VAS scale by Johnson EW et al (2001) at 7th and 14th day.	7th and 14th day after flap surgery

Locations (1): TPCTs Terna Dental College
🇮🇳
Mumbai, MAHARASHTRA, India
TPCTs Terna Dental College
🇮🇳Mumbai, MAHARASHTRA, India
Dr Shruti Patil
Principal investigator
7709744129
shrutipatil824@gmail.com