NCT00108017已完成3 期
Randomized, Multicenter, Dbl-Masked, Parallel Study Evaluating the 24 Hr. Diurnal Ocular Hypotensive Effect of 2% Dorzolamide Hydrochloride/0.5% Timolol Maleate Combo. Ophthalmic Sol. in Patients w/ Open Angle Glaucoma or Ocular Hypertension
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 330
- 主要终点
- 24 hour diurnal IOP reduction after 8 weeks of treatment
研究概览
简要总结
This study is comparing 2 medications for glaucoma and how effective they are at controlling glaucoma over the course of an entire day.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with glaucoma or ocular hypertension
排除标准
- •Other eye conditions
- •Poor vision
- •Recent eye surgery
- •Use of contact lenses
- •Nursing or pregnant women
- •Use of some other selected medications
- •Drug or alcohol abuse
- •Slow heart beat
- •Allergy or previous reaction to study drugs
结局指标
主要结局
24 hour diurnal IOP reduction after 8 weeks of treatment
时间窗: After 8 weeks of treatment
次要结局
- IOP reduction a) from baseline at 6 weeks; b) comparison with timolol; c) comparison day versus night(At 6 weeks)
研究者
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