Physical Activity Measured Through Accelerometers and Its Association With Endothelial Function in Young Patients With Fontan Physiology
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Heart Defects
- Sponsor
- University of Alberta
- Enrollment
- 25
- Locations
- 1
- Primary Endpoint
- Physical activity measured by accelerometers
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
This study will be a cross sectional assessment of physical activity as measured through accelerometers and its association with endothelial function of children with Fontan circulation and healthy age and gender matched controls who are followed at the University of Alberta - Stollery Children's hospital.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Children with Fontan physiology between the ages 24 months to 18 years at the Stollery Children's Hospital
- •Informed written consent obtained prior to enrolment
- •At least 6 months post Fontan procedure
Exclusion Criteria
- •Patient hospitalized within the previous 2 weeks
- •Patient unable to ambulate independently
- •Underwent coarctation of the aorta repair using a subclavian flap.
Outcomes
Primary Outcomes
Physical activity measured by accelerometers
Time Frame: Once consent/assent is obtained, participants will be asked to wear an Actigraph GT3X+ accelerometers for seven consecutive days, during waking hours.
Endothelial function measured by Digital Thermal Monitoring (DTM) via the automated, operator-independent protocol (VENDYS-6000, Endothelix Inc., Houston, TX) and the Endothelial Pulse Amplitude Test (Endo-PAT, Itamar Medical).
Time Frame: Once consent/assent is obtained, endothelial function will be measured one time during a routine clinical visit.
Secondary Outcomes
- Vascular health questionnaire(Once during routine clinical visit after informed consent/assent.)