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Collection of biomaterial for iPSCs to study the molecular mechanisms underlying Witteveen-Kolk syndrome

Recruiting
Conditions
Witteveen-Kolk syndrome
SIN3A syndrome
10083624
Registration Number
NL-OMON53284
Lead Sponsor
Radboud Universitair Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
3
Inclusion Criteria

- Written informed consent to participate in this study
- Having a (likely) pathogenic variant in SIN3A
- Clinical diagnosis of WitKoS as judged by the principal investigator
- Age >= 18 years

Exclusion Criteria

- Subjects who do not meet the inclusion criteria
- Subjects with another genetic variant (e.g. copy number variation, single
nucleotide variant) that most likely contributes to the neurodevelopmental
phenotype.

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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