Evaluation of mortality after drug-coated stent angioplasty of femoropopliteal lesions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 599
研究概览
简要总结
From 2010 to 2016 8,377 patients were treated with femoropopliteal lesions. This analysis included 599 patients. Three-hundred-three patients were treated with an uncoated device and 296 patients with a DES. The mean follow-up period was 51.80 ± 23.40 months (range 0–84). For the entire cohort mortality incidence was 32.3% after uncoated treatment and 22.6% after DES (p < .033). For the entire cohort multivariate logistic regression analysis revealed age (p < .001), diabetes mellitus (p = .010), renal insufficiency (p = .001) and RBC 4 (p < .001) as independent predictors for mortality. After propensity score matching mortality incidence was 32.5% after uncoated treatment and 24.1% after DES (p = .264). After propensity score matching, independent mortality predictors were age (p < .001), hyperlipidemia (p = .035), diabetes mellitus (p = .018) and RBC 4 (p < .001). Kaplan–Meier analysis showed that higher paclitaxel dosage was associated with lower mortality
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 110 Years(—)
- 性别
- All
入选标准
- •Patients who were treated with stent angioplasty at the University Heart Center Freiburg-Bad Krozingen (Bad Krozingen site) due to stenosis of the femoropliteal arteries.
排除标准
- •- Patients who had an intervention only iliacal or at the lower leg arteries
- •- Patients with an intervention due to stenosis of a femoropliteal/crural bypass
- •- Patients who have been treated with a paclitaxel-coated catheter iliacal or on the lower leg arteries in the same intervention
