跳至主要内容
临床试验/DRKS00019099
DRKS00019099已完成不适用

Evaluation of mortality after drug-coated stent angioplasty of femoropopliteal lesions

niversitäts-Herzzentrum Bad Krozingen0 个研究点目标入组 599 人开始时间: 2019年11月14日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
599

研究概览

简要总结

From 2010 to 2016 8,377 patients were treated with femoropopliteal lesions. This analysis included 599 patients. Three-hundred-three patients were treated with an uncoated device and 296 patients with a DES. The mean follow-up period was 51.80 ± 23.40 months (range 0–84). For the entire cohort mortality incidence was 32.3% after uncoated treatment and 22.6% after DES (p < .033). For the entire cohort multivariate logistic regression analysis revealed age (p < .001), diabetes mellitus (p = .010), renal insufficiency (p = .001) and RBC 4 (p < .001) as independent predictors for mortality. After propensity score matching mortality incidence was 32.5% after uncoated treatment and 24.1% after DES (p = .264). After propensity score matching, independent mortality predictors were age (p < .001), hyperlipidemia (p = .035), diabetes mellitus (p = .018) and RBC 4 (p < .001). Kaplan–Meier analysis showed that higher paclitaxel dosage was associated with lower mortality

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 110 Years(—)
性别
All

入选标准

  • Patients who were treated with stent angioplasty at the University Heart Center Freiburg-Bad Krozingen (Bad Krozingen site) due to stenosis of the femoropliteal arteries.

排除标准

  • - Patients who had an intervention only iliacal or at the lower leg arteries
  • - Patients with an intervention due to stenosis of a femoropliteal/crural bypass
  • - Patients who have been treated with a paclitaxel-coated catheter iliacal or on the lower leg arteries in the same intervention

研究者

发起方
niversitäts-Herzzentrum Bad Krozingen

相似试验