Predicting Early Treatment Termination (Dropout) and Post-treatment Clinical Outcome From Neuropsychological Functions in Abstinent Substance Use Dependent (SUD) Patients
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Exit reason
研究概览
简要总结
The aim of this project is to gain a more specific understanding of how different cognitive profiles predict residential treatment drop-out, treatment retention and post-treatment outcome in a population with Substance Use Disorder.
详细描述
This project collects the neuropsychological profile of residential SUD patients, in addition to treatment length, exit reason, hospital journal data and post-treatment clinical outcome data. The project aims to identify clinically relevant neurocognitive domains that predict treatment dropout and post-treatment clinical outcome. This will make it possible for future clinicians to focus their effort on neurocognitive functions most relevant for this particular patient group.
RESEARCH QUESTIONS:
- What neurocognitive domain (and sub-domain) are the strongest predictor of treatment drop-out and retention?
- What neurocognitive domain (and sub-domain) are the strongest predictor of post-treatment clinical outcome variables such as drug use, health and social integration.
- Will data on treatment length, age, gender, substance abuse history or psychiatric co-morbidity predict outcome independently, or in interaction with, the neuropsychological profile?
This longitudinal prospective cohort study aims for a continuous collection of neuropsychological data baseline and post-treatment follow-up data until 2030.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Substance Use Disorder (SUD) patients.
- •18 years or older.
- •Qualified to consent to research participation.
- •Able to speak and write in Norwegian.
排除标准
- •Not qualified to consent to research participation.
- •Insufficient understanding of Norwegian.
结局指标
主要结局
Exit reason
时间窗: On average 3 months
Reason for terminating residential SUD treatment (Treatment completed or Drop-out)
Treatment retention
时间窗: On average 3 months
Number of days in treatment
次要结局
- Substance use(1 year after neuropsychological assessment)
- Quality of Life(1 year after neuropsychological assessment)
- Psychological distress(1 year after neuropsychological assessment)
- Income(1 year after neuropsychological assessment)
- ADHD symptoms(1 year after neuropsychological assessment)
- Housing(1 year after neuropsychological assessment)
研究者
Espen Walderhaug
Principal Investigator
Oslo University Hospital