Comparision of ART(IVF or ICSI) outcome in two different induction ovulation protocols: Gonal-F versus Fostimon, in infertile patients with PCOD
Not Applicable
Completed
- Conditions
- Condition 1: female infertility. Condition 2: polycystic ovarian syndrome.female infertilitypolycystic ovarian syndrome
- Registration Number
- IRCT138901193636N1
- Lead Sponsor
- Tehran University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 160
Inclusion Criteria
age(20-35y), having at least 2 PCO criteria (Oligo or anovulation, oligomenorrhea or amenorrhea, hyperandrogenemia, hirsutism, volum of ovary>10ml, poly cystic ovaries), normal karyotype of couples, Exclusion criteria: age>35 or<20y, abnormal karyotype, other diseases causing anovulation(hypo or hyper gonadotropic hypogonadism, Cushing, hyperprolactinemia.), other causes of infertility, not having PCO criteria, history of poor response to gonadotropin induction.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of clinical pregnancy. Timepoint: 2 weeks after positive Bhcg. Method of measurement: sonography.;Rate of chemical pregnancy. Timepoint: 2 weeks after emberyo transfer. Method of measurement: serum bhcg.
- Secondary Outcome Measures
Name Time Method Rate of abortion. Timepoint: Every 2-4 weeks, based on patients' signs. Method of measurement: sonography.;Ongoing pregnancy. Timepoint: 12 weeks after positive BHCG. Method of measurement: sonography.;Numbers of follicles >18mm. Timepoint: 2-3 days after gonadotropin injection. Method of measurement: sonography.;Numbers of oocyts. Timepoint: in day of pick up. Method of measurement: Counting picked up oocyts.;Numbers of embryos. Timepoint: day of embryos transfer, 3 days after pick up. Method of measurement: counting embryos.;Endometrial thickness. Timepoint: At the day of HCG (Amp.) injection. Method of measurement: sonography.;Total numbers of gonadotropin ampoule administered. Timepoint: At final cycle. Method of measurement: Counting of ampoule administered.;Quality of embryo. Timepoint: 3 days after pick up. Method of measurement: by embryologist (grad A, B, C).;Numbers of embryos transferred. Timepoint: day of embryo transrfer. Method of measurement: counting of embryos transferred.