MedPath

Patient-reported Outcome Measures After Post-anesthesia Care Unit Delirium

Completed
Conditions
Neurocognitive Disorders
Delirium
Registration Number
NCT04168268
Lead Sponsor
Universitätsklinikum Hamburg-Eppendorf
Brief Summary

To assess self-reported cognitive function and health-related quality of life in patients with and without early postoperative delirium

Detailed Description

Neurocognitive disorders including postoperative delirium are a serious complication after surgery and anesthesia in the elderly. Postoperative delirium is an acute-onset diffuse brain dysfunction that is characterized by a fluctuating course of confusion, disorganized thinking, inattention, irritability, disturbances of the circadian rhythm, and disorders of consciousness. Post-anesthesia care unit (PACU) delirium occurs immediately after emergence from anesthesia and affects up to 45% of patients after elective surgery.

It is unclear, whether PACU delirium is associated with intermediated or long-term adverse outcomes including neurocognitive disorders or mortality. The aim of this prospective observational was to assess self-reported cognitive function and health-related quality of life in patients with and without PACU delirium three months after radical prostatectomy.

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
222
Inclusion Criteria
  • elective radical prostatectomy
  • >60 years
  • fluent in German
Exclusion Criteria
  • preexisting cognitive impairment
  • cerebrovascular disease

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Self-reported cognitive failuresthree months

Cognitive Failures Questionnaire

Secondary Outcome Measures
NameTimeMethod
Health-related quality of lifethree months

Short Form Health Survey 36

Trial Locations

Locations (1)

Department of Anesthesiology, University Medical Center Hamburg-Eppendorf

🇩🇪

Hamburg, Germany

© Copyright 2025. All Rights Reserved by MedPath