Influence of Post-anesthesia Care Unit Delirium After Radical Prostatectomy on Self-reported Cognitive Function and Health-related Quality of Life
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Delirium
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
- Enrollment
- 222
- Locations
- 1
- Primary Endpoint
- Self-reported cognitive failures
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
To assess self-reported cognitive function and health-related quality of life in patients with and without early postoperative delirium
Detailed Description
Neurocognitive disorders including postoperative delirium are a serious complication after surgery and anesthesia in the elderly. Postoperative delirium is an acute-onset diffuse brain dysfunction that is characterized by a fluctuating course of confusion, disorganized thinking, inattention, irritability, disturbances of the circadian rhythm, and disorders of consciousness. Post-anesthesia care unit (PACU) delirium occurs immediately after emergence from anesthesia and affects up to 45% of patients after elective surgery. It is unclear, whether PACU delirium is associated with intermediated or long-term adverse outcomes including neurocognitive disorders or mortality. The aim of this prospective observational was to assess self-reported cognitive function and health-related quality of life in patients with and without PACU delirium three months after radical prostatectomy.
Investigators
Eligibility Criteria
Inclusion Criteria
- •elective radical prostatectomy
- •\>60 years
- •fluent in German
Exclusion Criteria
- •preexisting cognitive impairment
- •cerebrovascular disease
Outcomes
Primary Outcomes
Self-reported cognitive failures
Time Frame: three months
Cognitive Failures Questionnaire
Secondary Outcomes
- Health-related quality of life(three months)