Remote Alcohol Monitoring to Facilitate Abstinence From Alcohol: Exp 2
- Conditions
- Alcohol Use Disorder
- Interventions
- Behavioral: Contingency management
- Registration Number
- NCT03942770
- Lead Sponsor
- Mikhail N Koffarnus
- Brief Summary
Directly reinforcing abstinence from alcohol with monetary incentives is an effective treatment for alcohol dependence, but barriers in obtaining frequent, verified biochemical measures of abstinence limit the dissemination of this treatment approach. As our feasibility study demonstrates, remote breathalyzer monitoring drastically improves the practicality of delivering an alcohol contingency management intervention. In Experiment 2, we will test whether the addition of remote abstinence incentives to treatment as usual improves outpatient treatment outcomes and prevents relapse following inpatient detoxification at a regional hospital system. We will also assess whether readmission rates are reduced using a newly developed smartphone app and breathalyzer.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 230
- Recently completed or currently completing an alcohol detoxification program through the Carilion Clinic or University of Kentucky Healthcare system.
- Meet DSM-V criteria for alcohol use disorder.
- Abstinent from alcohol at the time of consent.
- Alcohol use disorder is secondary to another substance use disorder.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Active Comparator: Group A (Intensive incentives) Contingency management Group A will have the opportunity to earn payments based on the results of their breathalyzer screens. Participants will receive a compliance incentive per submitted sample regardless of the results, but will also have the opportunity to earn more incentives for providing negative results. For the first 3 weeks, these additional incentives will scale based on the number of consecutive days of sustained negative samples. For the remaining weeks incentives will be based on a randomized "prize" drawing. Sham Comparator: Group C (Intensive incentives) Contingency management Group C serves as a direct control group to Group A and will follow the same incentive procedures, however participants will receive incentives regardless of the results of their samples. Sham Comparator: Group D (Price-based incentives) Contingency management Group D serves as a direct control group to Group B and will follow the same incentive procedures, however participants will receive incentives regardless of the results of their samples. Active Comparator: Group B (Prize-based incentives) Contingency management Group B will have the opportunity to earn payments based on the results of their breathalyzer screens. Participants will receive a compliance incentive per submitted sample regardless of the results, but will only have the opportunity to earn more incentives based on a randomized "prize" drawing if they submit a negative sample.
- Primary Outcome Measures
Name Time Method Pattern of abstinence from alcohol during intervention up to 66 weeks Breathalyzer assessments will be collected during the treatment period. This outcome measure will consist of the percentage of days without alcohol use as detected by the breathalyzers.
Time to relapse A total of 12 assessment sessions spanning over a 66 week period For this outcome, we will conduct survival analyses to compare relapse across study groups.
Treatment acceptability A total of 12 assessment sessions spanning over a 66 week period Participant ratings of treatment acceptability on a customized Treatment Acceptability questionnaire will be collected during assessment sessions. Each question will be scored from 1 (low) to 4 (high) and will assess distinct components of the treatment. Questions will be interpreted and scored individually and not be summed together.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
University of Kentucky Healthcare
🇺🇸Lexington, Kentucky, United States
Virginia Tech Carilion
🇺🇸Roanoke, Virginia, United States