Safety evaluation and effect of consumption of Isochrysis gabana and dill tea against oxidative stress in volunteers

Phase 1

Completed

• Conditions: Healthy conditions; Isochrysis gabana; Dill; oxidative stress

• Registration Number: TCTR20201223004
• Lead Sponsor: Agricultural Research Development Agency (ARDA)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-23
• Study Completion: 2021-07-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

1.Aged between 40-65 years old
2.Body Mass Index (BMI) less than 25 kg/m2
3.Not vegetarian volunteers

Exclusion Criteria

1.Volunteers who have serious physical illness such as cardiovascular diseases, respiratory diseases, neuropsychological diseases, head injury, diabetes mellitus, liver disease, cancer, autoimmune diseases and psychological disorder
2.Volunteers who require supplements or herbals within 2 months before participating in this study
3.Smoking more than 10 pieces/day
4.Alcohol addiction

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oxidative stress markers (MDA, CAT, SOD, GPx) 8 weeks Elisa method

Secondary Outcome Measures

Name	Time	Method
The changes of hematological and clinical chemistry parameters 8 weeks laboratory,Phenolic compounds and Flavonoids 8 weeks laboratory,Homeostasis Model Assessment Insulin Resistance (HOMA-IR) and Insulin 8 weeks laboratory,Atherosclerosis index (AI), Atherogenic index of plasma (AIP) and Oxidized LDL 8 weeks laboratory,Stool examination (PH, Total lactic acid, Bifidobacterial, Short chain fatty acid) 8 weeks laboratory,Electrocardiogram 8 weeks electrocardiography equipment,Anxiety, depression and insomnia evaluation using questionnaire 8 weeks Questionair