A Prospective Observational Study to Explore Treatment Regimens and Clinical Outcomes of the NSCLC Patients With Different Driver Genes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Non-small Cell Lung Cancer
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
- Enrollment
- 750
- Locations
- 1
- Primary Endpoint
- Differences in overall survival rates
- Last Updated
- 7 years ago
Overview
Brief Summary
A single-center, non-interventional prospective observational study in the NSCLC patients with different driver genes
Detailed Description
The trial was designed as a single-center non-interventional prospective observational study to explore clinical treatments of the NSCLC patients with different driver genes, the impact factors of patient survivals, and the relevance of gene types, clinical treatments, and distribution of gene types. The follow-up visits, interactions between the investigators and patients, patient questionnaires/quality of life, and other patient information will be uploaded via mobile APP, and webchat every three months.
Investigators
Jianxing He
Professor
The First Affiliated Hospital of Guangzhou Medical University
Eligibility Criteria
Inclusion Criteria
- •The patients with lung cancer who were performed with next-generation sequencing (NGS) technology from 2015 to 2017;
- •The patients who were at least 18 years;
- •The pathologically diagnosed patients with non-small cell lung cancer (NSCLC)
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Differences in overall survival rates
Time Frame: 2018-2022
Differences in overall survival rates of the NSCLC patients with various gene types
Secondary Outcomes
- Relevance of gene types(2018-2022)
- Interaction impact between gene types and treatment modalities or regimens on disease-free survivals(2018-2022)
- Impacts of progression-free survivals(2018-2022)
- Statuses of clinical treatment regimens(2018-2022)
- Impacts of disease-free survivals on gene types(2018-2022)
- Relevance of overall survival rates and gene types(2018-2022)
- Impact factors of overall survivals(2018-2022)