Association Between Body Mass Index and High-flow Cannula Therapy Success in Patients With Severe Covid 19 Related Pneumonia. Retrospective Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 303
- 试验地点
- 1
- 主要终点
- Primary outcome
研究概览
简要总结
Patients over 18 years of age who are admitted to the Intermediate Care Unit of the Clinica del Country and the Clinica la Colina, with symptoms suggestive of severe pneumonia secondary to COVID-19 infection and acute hypoxemic respiratory failure. The primary outcome will be to determine the relationship between body mass index and high-flow cannula therapy success defined as: No need for mechanical ventilation.
详细描述
All adult patients over 18 years of age admitted to the intermediate care service of the participating center with suspected SARS-CoV-2 pneumonia will be considered as potential candidates for the study.
The medical records of patients in our cohort who require high-flow cannula therapy and who met all the inclusion criteria and none of the exclusion criteria will be reviewed.All data will be processed and analyzed using the SPSS 26 software once the study is completed. study sample
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over 18 years of age.
- •Diagnosis of severe pneumonia secondary to COVID-19 infection and acute respiratory distress syndrome, defined by upper and lower respiratory symptoms plus positive C-reactive protein test for COVID-
- •Patient admission to the Clinical del Country and Clinica de la Colina intermediate care units.
- •Oxygen therapy by high-flow system (high-flow cannula) requirement.
- •Anthropometric data availability upon admission to our facilities.
排除标准
- •Patients with a survival expectancy of less than 12 months according to the Charlson scale categorization or patients with oncological pathology.
- •Patients under 18 years of age.
- •Pregnant women.
- •Patients with cardiogenic pulmonary edema.
- •History of chronic liver disease or cirrhosis Child - Pugh C.
- •Patients with contraindications to high-flow cannula therapy initiation.
- •Patients with respiratory, hemodynamic and neurological indications that contraindicate HFNC initiation.
结局指标
主要结局
Primary outcome
时间窗: 1 year.
To determine the relationship between body mass index "BMI" calculated by kg / m2 (BMI was classified in the following categories: normal weight: 18.5-24.9 kg / m2, overweight: 25-29.9 kg / m2, and obesity: ≥ 30 kg / m2) and high-flow cannula therapy success defined as: No need for mechanical ventilation.
次要结局
- Demographic and laboratory characteristics(1 year)
- Body mass index as a predictor(1 year)
- Body mass index and HFNC success(1 year)
- Mortality(1 year)
- Hospital stay.(1 year)
研究者
Carlos Augusto Celemín Florez, MD.
Principal Investigator.
Clínica del country