NL-OMON35377
Completed
Not Applicable
The role of intestinal microbiota composition and intestinal permeability in the development of (complicated) diverticular disease. - Pathophysiology of diverticular disease.
Medisch Universitair Ziekenhuis Maastricht0 sites210 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Outpocketings of colonic mucosa
- Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Enrollment
- 210
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Age \>\= 50 years and \<\= 75 years
- •\- Scheduled for colonoscopy
- •\- Written informed consent
- •\- Patient group: The presence of diverticulosis, diagnosed during the scheduled conoloscopy
- •\- Control group: During the scheduled colonoscopy, diverticulosis or other gastrointestinal and liver diseases are absent. In other words, the colonoscopy is qualified as a \*normal\* colonoscopy.
Exclusion Criteria
- •\- Age \< 18 years
- •\- Presence of gastrointestinal and liver diseases, such as inflammatory bowel disease
- •\- Use of NSAID\*s and proton pump inhibitors, during the 5\-day time period prior to endoscopy
- •\- Alcohol intake above 14 consumptions per week for males and 7 consumption per week for females
- •\- (Sub)total colectomy or hemicolectomy.
- •\- Refusal to participate in this study
Outcomes
Primary Outcomes
Not specified
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