A study on association of inflammatory ,genetic and epigenetic markers with Kellgren Lawrence grading in post traumatic osteoarthritis of knee
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 170
- Locations
- 1
- Primary Endpoint
- We can initiate treatment and screening procedures in handling osteoarthritis subsequent to trauma
Study Overview
Brief Summary
The study participants are inducted into the study after getting written informed consent. They are identified by the consultants in the departments of Arthroscopy and Sports medicine. Individuals in the age group of 20-50 years who give history of injury to the knee joints in less than 3 months are included. All the participants are subjected to clinical examination, objective pain scoring, standard knee outcome score visual-analogue scale (VAS) and WOMAC .X ray will be taken .Blood and urine samples will be collected.The samples will be analysed for biomarkers .Statistical analysis will be done .
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 20.00 Year(s) to 50.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •H/O Knee injury within 3 months.
Exclusion Criteria
- •History auto immune diseases Any ohter chronic medical ilness Post menopausal women H/O Viscosupplementaion or vit D.
Outcomes
Primary Outcomes
We can initiate treatment and screening procedures in handling osteoarthritis subsequent to trauma
Time Frame: Baseline,6 months and 12 months
Secondary Outcomes
- Normal joint or OA joint(12 months)
Investigators
Keerthy Rethinam M
Sri Ramachandra Institute of higher education and research