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Clinical Trials/NCT00725426
NCT00725426CompletedPhase 1

A Study to Examine the Potential Effect of Rifampin on the Pharmacokinetics of Bosutinib When Administered Concomitantly to Healthy Subjects

Wyeth is now a wholly owned subsidiary of Pfizer0 sites24 target enrollmentStarted: July 2008Last updated:
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Conditions
Interventions
Drugs

Trial Snapshot

Phase
Phase 1
Status
Completed
Sponsor
Enrollment
24
Primary Endpoint
Pharmacokinetics (plasma concentrations)
Study OverviewStudy DesignEligibility CriteriaArms & InterventionsOutcomesInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Study to examine whether rifampin has an effect on the pharmacokinetics of bosutinib.

Study Design

Study Type
Interventional
Allocation
Non Randomized
Intervention Model
Single Group
Masking
None

Eligibility Criteria

Ages
18 Years to 50 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Healthy men age 18-50
  • •Healthy women of nonchildbearing potential, age 18-50

Exclusion Criteria

  • Not provided

Arms & Interventions

1

Experimental

Bosutinib

Intervention: Bosutinib (Drug)

Outcomes

Primary Outcomes

Pharmacokinetics (plasma concentrations)

Time Frame: 4 weeks

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Sponsor Class
Industry

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