Use of Enhanced Recovery After Surgery (ERAS) in Minimizing Opioid Use for Patients Undergoing Thyroidectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- visual analog scale pain level
研究概览
简要总结
Pain control modalities were evaluated after thyroidectomy.
详细描述
Pain control modalities were evaluated after thyroidectomy. Patients were randomized to one of two pain control regimens. The control group received conventional opioid based post operative analgesia while the test group received an enhanced recovery after surgery (ERAS) based anesthesia with use of acetaminophen and non-steroidal anti-inflammatory drugs for the post operative period with opioid medications available for break through pain only. Pain scores (measured on visual analog scale) and opioid use (measured in morphine equivalent dose) were measured after completion of the operation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •thyroid disease
排除标准
- •currently on opioid pain medications
- •on opioid pain meds in last 30 days
- •cannot take non-opioid medications
- •require more extensive operation than thyroidectomy
研究组 & 干预措施
Acetaminophen and hydrocodone based pain control
Patients receive acetaminophen 650mg every 4 for pain level 1-3, hydrocodone/acetaminophen 5/325mg every 4 for pain level 4-6, or hydrocodone/acetaminophen 10/650mg every 4 for pain level 7-10 on as needed basis.
干预措施: Acetaminophen and hydrocodone based pain control (Other)
Acetaminophen and ibuprofen based pain control
Patients receive standing dose of acetaminophen 650mg every 8 hours and ibuprofen 800mg every 8 hours with alternating ibuprofen and acetaminophen every 4 hours.
干预措施: Acetaminophen and ibuprofen based pain control (Other)
结局指标
主要结局
visual analog scale pain level
时间窗: 7 days post operatively
Pain level from 0 (no pain) to 10 (worst pain imaginable).
visual analog scale pain level
时间窗: 1 hour post operatively
Pain level from 0 (no pain) to 10 (worst pain imaginable).
visual analog scale pain level
时间窗: 6 hour post operatively
Pain level from 0 (no pain) to 10 (worst pain imaginable).
visual analog scale pain level
时间窗: 24 hour post operatively
Pain level from 0 (no pain) to 10 (worst pain imaginable).
次要结局
- opioid use(with the first 24 hours post operatively)