Home-based exercise and motivational programme before and after liver transplantation: ExaLT Trial
- Conditions
- Exercise before and after liver transplantSurgery
- Registration Number
- ISRCTN13476586
- Lead Sponsor
- niversity of Birmingham
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 269
1. Adult Patients (aged 18 years or over)
2. Patients listed for a cadaveric, primary liver transplantation (LT) at QEUHB or the RFH
3. Being an out-patient at the time of baseline trial visit (consent)
1. Patient listed for Liver Transplant for any of the following reasons:
1.1. Super-urgent Liver Transplant (according to the Kings College criteria)
1.2. Multi-organ transplantation (e.g. combined liver and kidney transplant)
1.3. Live-related donor Liver Transplant
1.4. Re-graft Liver Transplant
2. Patients with an inability to safely comply with the exercise intervention due to the following conditions:
2.1. Severe hepatic encephalopathy (defined as grade 3 or 4; as judged by the principal or nominated co-investigators)
2.2. Oxygen-dependent hepato-pulmonary syndrome
3. Patients without liver failure, including:
3.1. Liver cancer in the absence of cirrhosis
3.2. Polycystic liver disease
3.3. Rare metabolic/genetic conditions (e.g. glycogen storage disorders)
4. Refusal or lacks capacity to give informed consent to participate in the trial, at the point of study visit 1
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Physical component score (PCS) from the short form-36 version 2.0 (SF-36v2) health-related QoL questionnaire at 24 weeks post LT (scale 0-100).
- Secondary Outcome Measures
Name Time Method