Inflammation and Steatosis: the Role of Alpha-defensin

• Conditions: Inflammation; Fatty Liver

• Registration Number: NCT03358420
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

The aim of this study is to examine the correlation between the severity of non-alcoholic steatohepatitis/non alcoholic fatty liver disease (NASH/NAFLD) in naïve and hepatitis C (HCV) positive patients and the amplitude of alpha-defensin immunohistochemical staining in liver biopsy.

Detailed Description

Not available

Study Timeline

• Status Verified: 2017-11
• Study First Submitted: 2017-11-27
• Study First Submitted QC: 2017-11-27
• Last Update Submitted: 2017-11-27
• Study First Posted: 2017-11-30
• Last Update Posted: 2017-11-30
• Study Start: 2017-12
• Primary Completion: 2018-07
• Study Completion: 2018-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Fatty liver disease patients with liver biopsy

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Amplitude of immunohistochemical stain	Six months	The amplitude of each slide will be graded from 1-4

Trial Locations

Locations (1)

Hille Yaffe Medical Center; 🇮🇱 Hadera, Israel