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Effects of lipid lowering on endothelial functio

Not Applicable
Recruiting
Conditions
Diseases of the circulatory system
Registration Number
KCT0001730
Lead Sponsor
Wonkwang University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
81
Inclusion Criteria

1) Unstable angina, non-ST-segment elevation acute coronary syndrome receiving optimal reperfusion therapy
2) Evidence of coronary artery disease
3) low density lipoprotein cholesterol >70mg/dl, triglyceride <500mg/dl
4) agree to informed consent

Exclusion Criteria

1) contraindication to statin therapy
2) pregnant women
3) life expectancy less than 2 years
4) abnormal renal, liver function
5) prescibed other lipid lowering medication (fibrate, omega 3, niacin)

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
flow-mediated vasodilation in each groups
Secondary Outcome Measures
NameTimeMethod
ipid profile (total cholesterol, triglyceride, LDL-C, HDL-C) in each groups;brachio-ankle pulse wave velocity in each groups
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